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DEN vs
SF

Denver Broncos vs San Francisco 49ers

October 4, 2026 ยท 4:25 PM ET ยท Levi's Stadium
DEN โ€”  ยท  SF 1-0

SportsFBI Model

Projects San Francisco 49ers to win โ€” 62% confidence
Market agrees (+5pp) Market-implied score: SF 25 ยท DEN 22 Blowout chance (14+ margin): 31%
SF Home field advantage
SF Home team off bye

Betting Lines DraftKings

Spread
DEN +2.5 (-110)
SF -2.5 (-110)
Total (O/U)
Over 46.5 (-110)
Under 46.5 (-110)
Moneyline
DEN +114
SF -135

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All Key Suspects with verdict breakdowns, matchup conditions, sharp money signals, live lineup tracking, and player prop edges โ€” available in the BlowOutAlert workspace.

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