NFL Final Intelligence
Arizona Cardinals vs San Francisco 49ers β Recap
September 27, 2026 Β· Levi's Stadium Β· View Preview
Game Recap
The San Francisco 49ers withstood a determined fourth-quarter comeback attempt from the Arizona Cardinals, repeatedly answering late scoring drives to secure a hard-fought victory at home. After establishing an early lead, San Francisco's offense, spearheaded by quarterback Brock Purdy, consistently delivered crucial responses in the face of Arizona's persistent surge, which saw the Cardinals put up 17 points in the final frame. The 49ers, who entered the contest as heavy favorites, relied on their offensive firepower to keep the resilient Cardinals at bay.
San Francisco began by asserting control, with Brock Purdy connecting with Mike Evans on a short pass that was lateralled to Deebo Samuel for a stunning 80-yard opening touchdown in the first quarter. Purdy extended the lead further in the second quarter with a 23-yard strike to Mike Evans, putting the 49ers up 14-0. Arizona managed two field goals from Chad Ryland, but Eddy Pineiro added one for San Francisco, making it 17-6 at halftime. Christian McCaffreyβs 1-yard rush in the third pushed the advantage to 23-6 before Arizona began its rally with a 5-yard Michael Wilson touchdown reception from Jacoby Brissett, cutting the deficit to 23-13.
The fourth quarter proved pivotal, with Arizona launching a significant offensive effort to close the gap. Jeremiyah Love's 1-yard touchdown reception from Jacoby Brissett narrowed the margin to just three points at 23-20. However, Purdy consistently delivered clutch plays for the 49ers, responding with a 10-yard touchdown pass to George Kittle to momentarily extend their lead. Jacoby Brissett then scrambled for a 1-yard touchdown run, bringing the Cardinals to within two points at 29-27. Purdy found Kittle again from 20 yards out for another touchdown, providing the decisive buffer for San Francisco as they absorbed Arizona's best efforts, even with a final Chad Ryland field goal for the Cardinals.
Ultimately, the 49ers' ability to match the Cardinals' offensive firepower, particularly Brock Purdy's four touchdown passes, was the key to their victory on a day when Arizona refused to yield. The San Francisco 49ers now stand at 3-0, while the Arizona Cardinals fall to 1-2.
How the Prediction Fared
Pregame, the market favored the San Francisco 49ers (-625, 83% implied) over the Arizona Cardinals. Final: the San Francisco 49ers won 36β30.
SportsFBI's model favored the San Francisco 49ers (72% confidence). Final: the San Francisco 49ers won 36β30.
Standouts
Full box score, defensive stats, and every player's line are available in the BlowOutAlert workspace.
Biggest Quarter
The Arizona Cardinals scored 17 points in the 4th quarter β the biggest single quarter of the game.
More NFL Results β Sunday, September 27, 2026
























Sharper Picks Start Here
Live odds, Key Suspects, player props, DFS rankings, and real-time game tracking β all in one workspace built for serious bettors and DFS players.

