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New England Patriots vs Buffalo Bills

October 4, 2026 · 1:00 PM ET · Highmark Stadium
NE 0-1 · BUF —

SportsFBI Model

Projects Buffalo Bills to win — 65% confidence

Market agrees (+3pp) Market-implied score: BUF 26 · NE 23 Blowout chance (14+ margin): 31%

BUF Home field advantage

NE Away team off bye

BUF Away team key injuries

Betting Lines DraftKings

Spread

NE +3.0 (-110)

BUF -3.0 (-110)

Total (O/U)

Over 49.5 (-110)

Under 49.5 (-110)

Moneyline

NE +140

BUF -166

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